What are the Gallbladder Cancer Symptoms? The onset of gallbladder cancer is preceded by a general loss of appetite. A gallbladder cancer diagnosis often occurs in the upper right abdominal area. Symptoms of gallbladder cancer may also include jaundice, a condition characterized by excessive levels of the substance bilirubin in the blood. People who develop this condition usually experience intense itching, a yellowish skin appearance and the whites of their eyes. Light colored or gray stools are also a sign of bilirubin buildup.
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There are two stages of gallbladder cancer: stage 0 and stage IIIA. Stage 0 describes a tumor located within the gallbladder, and stage II is the cancer that has spread to the liver and nearby lymph nodes. Stage IIIA is the most advanced stage of the disease, and it involves the spread of the cancer beyond the gallbladder to distant organs. While rare, gallbladder cancer symptoms can occur when the cancer has spread beyond the gallbladder.
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When the gallbladder becomes inflamed, it can block the bile ducts. This prevents bile from draining into the intestines, causing jaundice. When bile is blocked, the bilirubin in the bile settles in various parts of the body, including the skin and white parts of the eyes. Additionally, gallbladder cancer may cause enlargement of the gallbladder, which can cause pain and discomfort in the abdomen. If this is the case, gallbladder cancer symptoms may also include abdominal swelling, fever, loss of appetite, weight loss, and severe itching.
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In addition to the bilirubin test, blood tests for bilirubin levels are necessary to confirm the diagnosis. High levels of bilirubin can indicate problems with the gallbladder, and abnormal liver function may also be an indicator of gallbladder cancer. When a gallbladder cancer diagnosis is suspected, imaging tests such as computed tomography (CT) and magnetic resonance cholangiopancreatography (MRI) are conducted to confirm the diagnosis.
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Although there are several risk factors for gallbladder cancer, it is difficult to determine whether a particular risk factor will lead to the disease. Long-term inflammation of the gallbladder is a risk factor. Having gallstones increases the risk, especially for those with large stones. Although gallstones are very common and rare in people with gallbladder cancer, having gallstones increases the likelihood of developing gallbladder cancer.
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When symptoms of gallbladder cancer are discovered early, surgery can remove the entire gallbladder and improve quality of life. In some cases, patients may be able to benefit from palliative treatments such as chemotherapy or clinical trials. Information on ongoing clinical trials can be found on the National Cancer Institute website. If gallbladder cancer is diagnosed in a Stage II or lower, surgery may be the only treatment. However, this type of surgery has high morbidity and can also cause organ failure.
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A biopsy is usually the only way to confirm a diagnosis of gallbladder cancer. It is a procedure that involves the removal of a small sample of fluid or tissue from the affected area and examining it under a microscope. A biopsy can help diagnose the type of cancer and whether it has spread. A biopsy may also help determine if the cancer has spread throughout the body. If it has spread, it can be treated successfully.
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Often the symptoms of gallbladder cancer mimic those of gallstones. If you notice any of these symptoms, contact your healthcare provider as soon as possible. The early detection of gallbladder cancer is crucial to improve patient care and outcome. The sooner you detect gallbladder cancer, the more likely you are to survive the disease. But before undergoing surgery, you should consult your doctor about any concerns you may have.
