The pain associated with bone cancer may be a red flag for a possible underlying condition, such as bone sarcoma. It can also lead to swelling or numbness in the affected area. These symptoms may worsen with movement or can be mistaken for growth pain. As a result, a timely diagnosis may be difficult. Other signs of bone cancer include joint pain and stiffness, and a reduced range of motion.
The most common symptom of bone cancer is pain in the affected area. Pain usually begins as tenderness in the area and worsens with activity or use. A visible lump may also form in the affected area, making the joint painful to move. If the pain continues or worsens, it is most likely a symptom of bone cancer. It is best to visit a doctor as early detection is the best way to avoid complications.
Osteoblasts and osteoclasts produce a variety of cytokines that induce inflammation in the affected area. These cells stimulate osteoblasts and osteoclasts to produce inflammatory responses and release pro-inflammatory cytokines. They can also cause pain in adjacent areas of the body. This phenomenon is known as reflective pain. This type of pain is the result of damage to the nerves in the affected bone.
Patients who have tumors in the bones may also experience “breakthrough” pain. This is a temporary, recurrent episode of pain that is more intense than the background pain. Breakthrough pain poses a larger therapeutic challenge than background pain, which is often considered an underlying condition. Because it is not caused by a specific cause, breakthrough pain is a common symptom of cancer in the bone. And it is not the only type of pain.
Treatments for bone cancer can vary, and new molecular pathways may lead to new therapies. For instance, radiation therapy for cancer patients may increase the risk of bone cancer. If the cancer has spread to the bones, it may cause swollen areas and press on the bone nerves. Steroids may reduce the swelling and pain in these areas. While steroids may cause some side effects, they are often used to treat other conditions, such as a broken bone or an infection.
If your symptoms are associated with the bone, X-rays can be helpful to confirm the diagnosis. Bisphosphonates bind to damaged bone and inhibit further damage. Bisphosphonates may be prescribed in addition to radiotherapy or pain-relieving drugs. However, it is important to visit a bone cancer specialist if your symptoms are related to the bone. Bisphosphonates are effective treatments for pain and may reduce the risk of bone fractures.
In some cases, bone cancer patients may need surgery. After the surgery, metal pins or plates may be inserted into the bone under a general anaesthetic. This will reduce the chance of breaking the bone and provide support during the recovery period. Additionally, a type of cement may be used to fill in the affected area. This will strengthen the bone and make it less painful. After the surgery, some patients may receive radiotherapy for the bone cancer to further reduce the chances of the cancer returning.